Super Actilis (Tadalafil/Dapoxetine)

What is Super Actilis (Tadalafil/Dapoxetine)?

Super Actilis is a combination oral tablet containing both tadalafil and dapoxetine, manufactured by Actiza Pharmaceutical Pvt. Ltd. Tadalafil addresses erectile dysfunction (ED) by supporting blood flow during sexual stimulation, while dapoxetine is a fast-acting selective serotonin reuptake inhibitor (SSRI) specifically developed for premature ejaculation (PE). Packaged as 10 tablets per strip at a 20 mg/60 mg strength, it's designed for men who have been assessed for both conditions rather than just one. If your primary concern is ED alone, our tadalafil-only Actilis 20 mg (Tadalafil) may be the more appropriate starting point.

Active Ingredients

Tadalafil (20 mg)

Tadalafil belongs to the phosphodiesterase type 5 (PDE5) inhibitor class and is one of the most widely studied treatments for erectile dysfunction. It's known for a notably long duration of action compared with some other ED medications, which is covered in more depth in our article on Phosphodiesterase Type 5 (PDE5) Inhibitors.

Dapoxetine (60 mg)

Dapoxetine is a short-acting SSRI developed specifically for on-demand use in premature ejaculation, unlike traditional SSRIs which are typically prescribed for daily, ongoing use in depression or anxiety. It works by increasing the time it takes to reach ejaculation, giving more control during sexual activity.

How Super Actilis Works

These two ingredients act through different mechanisms, which is exactly why they're paired rather than substituted for one another.

Tadalafil's Mechanism

Tadalafil inhibits the PDE5 enzyme in penile tissue, allowing nitric oxide to accumulate and relax surrounding blood vessels. This increases blood flow during sexual stimulation, supporting a firmer and more sustained erection. It does not create arousal by itself — stimulation is still required.

Dapoxetine's Mechanism

Dapoxetine works on serotonin reuptake in the central nervous system, which helps delay the ejaculatory reflex. Because it's absorbed and cleared from the body relatively quickly compared with standard SSRIs, it's suited to as-needed use before sexual activity rather than a daily regimen.

Together, the combination is intended to address both the physical blood-flow component of ED and the neurological timing component of PE in a single tablet.

Benefits

Men consider Super Actilis for a few practical reasons:

• Addresses two related concerns with one prescription rather than managing separate medications
• Tadalafil's long-acting profile reduces pressure around precise timing
• Dapoxetine offers rapid onset suited to on-demand use
• A single, standardized dosing format simplifies use compared with combining two separate tablets
• Manufactured to consistent pharmaceutical standards

Uses

Super Actilis is intended for:

• Adult men who have been diagnosed with both erectile dysfunction and premature ejaculation
• Cases where treating ED alone hasn't resolved concerns around ejaculatory control
• Use within a broader sexual health management plan under medical supervision

It is not appropriate for men who have only one of these two conditions, since taking dapoxetine without a genuine indication offers no benefit and only adds unnecessary exposure to a second active ingredient. A comparable tadalafil-only option, such as our Tadalafil Dapoxetine Tablet, is worth discussing with your doctor if you're unsure which combination or strength best matches your situation.

Dosage and Administration

Dosage should always be confirmed by a licensed healthcare provider, since both ingredients carry their own considerations.

Because dapoxetine has a different absorption profile than tadalafil alone, timing recommendations for this combination product may differ slightly from tadalafil-only tablets — another reason a doctor's guidance matters more here than with a single-ingredient product.

Who Should Take It

Super Actilis may be appropriate for adult men who:

• Have a confirmed diagnosis of both erectile dysfunction and premature ejaculation
• Have been medically cleared for sexual activity, including any relevant cardiovascular assessment
• Do not have a history of conditions that specifically contraindicate SSRIs, such as certain mood disorders requiring other medication

It is not suitable for women, minors, or men taking nitrate medications or other SSRIs/SNRIs, given the risk of interaction. A full medical evaluation should precede treatment, particularly given the dual-ingredient nature of this product.

Possible Side Effects

Because Super Actilis combines two active ingredients, side effects can reflect either component:

• Headache
• Dizziness
• Nausea
• Facial flushing
• Fatigue or drowsiness
• Indigestion

Dapoxetine in particular has been associated with dizziness and fainting in some men, especially if standing up quickly after dosing — a precaution worth taking seriously given the added SSRI component that tadalafil-only products don't carry. Seek immediate medical attention for an erection lasting more than four hours, sudden vision or hearing changes, or symptoms of serotonin syndrome such as agitation, rapid heartbeat, or high fever.

Precautions

Before starting Super Actilis:

• Disclose your complete medical history, including any history of depression, anxiety, or other mental health conditions
• Avoid standing up too quickly after taking a dose, given dapoxetine's association with dizziness
• Avoid combining with alcohol, which can intensify side effects from both ingredients
• Never combine with other SSRIs, SNRIs, or MAOIs without explicit medical guidance

For general, independent background on premature ejaculation and its treatment options, this national health service overview is a useful, non-commercial resource.

Drug Interactions

This combination product carries interaction risks from both ingredients:

• Tadalafil-related: nitrate medications (risk of dangerous blood pressure drops), alpha-blockers, and other PDE5 inhibitors
• Dapoxetine-related: other SSRIs, SNRIs, MAOIs, and certain other serotonergic medications, due to the risk of serotonin syndrome
• Shared risk: medications that affect liver enzyme processing, which can alter how both ingredients are metabolized

Always provide your prescriber with a complete list of current medications and supplements before starting treatment, since this combination has more potential interaction points than a tadalafil-only tablet.

Storage Instructions

• Store at room temperature, away from direct light and moisture
• Keep tablets in their original strip packaging until use
• Store well out of reach of children and pets
• Discard tablets after the printed expiration date

Frequently Asked Questions

1. What's the difference between Super Actilis and tadalafil-only tablets?
Super Actilis combines tadalafil for erectile dysfunction with dapoxetine for premature ejaculation, addressing both conditions in one tablet, whereas standard tadalafil tablets only target ED.

2. Can I take Super Actilis if I only have ED and not PE?
It's generally intended for men diagnosed with both conditions. If PE isn't a concern for you, a tadalafil-only option like Actilis 20 mg (Tadalafil) may be more appropriate — this should be confirmed with your doctor.

3. How long does Super Actilis take to work?
General guidance suggests taking it roughly 1 to 3 hours before activity, though individual response can vary based on both the tadalafil and dapoxetine components.

4. Is a prescription required for Super Actilis?
Yes. Given the dual-ingredient formulation and dapoxetine's specific precautions, a licensed healthcare provider should confirm both diagnoses and appropriate use before you begin treatment.

5. Can Super Actilis be combined with alcohol?
This is best avoided. Alcohol can intensify side effects from both tadalafil and dapoxetine, including dizziness and low blood pressure.

6. Are there alternatives if this combination isn't the right fit?
Yes. Options include our Tadalafil Dapoxetine Tablet at a different strength ratio, or browsing tadalafil-only options in our Erectile Dysfunction category if PE isn't part of your diagnosis.

Conclusion

Super Actilis (Tadalafil/Dapoxetine) offers a combined approach for men managing both erectile dysfunction and premature ejaculation, built around two well-studied active ingredients rather than a single-purpose formula. Because it carries a broader set of precautions and interaction considerations than tadalafil alone, it's especially important that this option be discussed with — and confirmed by — a licensed healthcare provider rather than chosen based on assumption. For further reading on managing Cialis-based treatment more broadly, our guide to affordable Cialis alternatives covers related options.

Medical Disclaimer: This content is provided for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting Tadalafil, Dapoxetine, or any new medication, especially if you have underlying health conditions or take other medications.